[HTML][HTML] High prevalence of genotypes associated with sulfadoxine/pyrimethamine resistance in the rural area of Fougamou, Gabon

FM Boukoumba, JB Lekana-Douki, PB Matsiegui… - … Antimicrobial Resistance, 2021 - Elsevier
chloroquine resistance transporter (Pfcrt) were described [2]. … was estimated using the
microscopic Lambaréné method [31]. … Plasmodium falciparum infection induced a decrease in red …

Development and implementation of molecular methods to genotype Plasmodium falciparum in uncomplicated malaria and severe malarial anemia in Gabon

B Mordmüller - 2020 - tobias-lib.ub.uni-tuebingen.de
… One possible explanation for the halted decline in malaria … with Plasmodium falciparum
malaria in Lambaréné, Gabon”. … over time (our result compared with the result of Kun et al 1998

Ex vivo drug sensitivity assay on Plasmodium malariae in Lambaréné

AHW Hoffmann - 2023 - tobias-lib.ub.uni-tuebingen.de
… vivax strains developed resistance, the application of CQ decreased drastically. CQ is a 4-…
Lambaréné is a small town around 250 km southeast of Libreville, the capital of Gabon. It is …

Resistance to antimalarials: a pharmacogenomics approach for both parasite and human host

L Pernaute-Lau - 2022 - repositorio.ul.pt
resistance selection. Therefore, the dual aim of this thesis is to identify new genetic causality
for Plasmodium falciparum resistance … pharmacogenes of a Gabonese population. Out of …

[HTML][HTML] … of sustainable research excellence with a global perspective on infectious diseases: Centre de Recherches Médicales de Lambaréné (CERMEL), Gabon

M Ramharter, ST Agnandji, AA Adegnika, B Lell… - Wiener Klinische …, 2021 - Springer
… increasing drug resistance of Plasmodium falciparum malaria in … the first to report chloroquine
resistance in Gabon in 1984 [1]. … -chloroquine and clindamycin-quinine for the treatment of …

Counter-selection of antimalarial resistance polymorphisms by intermittent preventive treatment in pregnancy

…, E Uberegui, H Gupta, P Cisteró… - The Journal of …, 2020 - academic.oup.com
… 2010 and 2013 in Benin, Gabon, Kenya, and Mozambique to … Polymorphisms in the P
falciparum CQ resistance transporter … decreased selection in the case of negative cross-resistance

[HTML][HTML] Prevalence of malaria among febrile patients and assessment of efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated malaria …

…, SC Kobawila, JM Youndouka, LK Basco, P Ringwald… - Malaria Journal, 2022 - Springer
… of artemisinin-resistant Plasmodium falciparum strains in Africa… 2003 showed a rapidly
declining efficacy of amodiaquine and … level of chloroquine resistance and moderate resistance to …

Pharmacotherapy for artemisinin-resistant malaria

E Koehne, AA Adegnika, J Held… - Expert Opinion on …, 2021 - Taylor & Francis
… There is a fear of resistant Plasmodium falciparum emerging in … falciparum parasites with
decreased susceptibility/resistance … in Gabon in children with uncomplicated malaria reported a …

Mutations in Pfcrt and Pfmdr1 genes of Plasmodium falciparum isolates from two sites in Northcentral and Southwest Nigeria

CO Agomo, N Mishra, YA Olukosi, R Gupta… - Infection, Genetics and …, 2021 - Elsevier
… the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) gene and Plasmodium
falciparum multidrug resistance … , a significant decline in the early responses of childhood P. …

Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre …

B Ogutu, A Yeka, S Kusemererwa… - The Lancet Infectious …, 2023 - thelancet.com
Background Emergence of drug resistance demands novel antimalarial drugs with new
mechanisms of action. We aimed to identify effective and well tolerated doses of ganaplacide …